Friday, July 3, 2020

Wemmick Living Dual Existences in Victorian England - Literature Essay Samples

Through his novel Great Expectations, Charles Dickens emphasizes the perpetually domineering nature of 19th century England’s uncompromising class structure system. Dickens satirizes the socially vital and inflexible natures of this system through characters such as Mrs. Pocket, whose failure to realize her low-class status drives her to neglect her family and sensibility, and Mr. Pumblechook, who only respects main character Pip after he comes into a large inheritance. However, Dickens most effectively highlights the seriousness of one’s place in this society through Mr. Wemmick, whom Pip befriends in the novel’s second volume. Through this character, Pip learns not only how to separate the confinements of social stratification from a humble lifestyle, but also to appreciate the modest pleasures and lessons of his own â€Å"lowly† roots. Dickens uses Wemmick as a meaningful instrument to convey these important messages, and does so convincingly through hi s use of details to describe Wemmick’s home versus occupational lives, language to signify his change in tone between the two settings, and images to impart the extent to which Wemmick separates his different worlds.Dickens, masterful in the arts of amusing and meaningful description, uses a liberal supply of details in describing Wemmick’s beloved, if low class, dwelling and family life. Before Pip is introduced to Wemmick’s alternate suburban society, he only interacts with Wemmick in a strictly professional capacity; thus, he has no notion of Walworth, Wemmick’s alternate-reality fortress in which Wemmick consistently takes on an , emancipated identity. Pip, somewhat ashamed of his own beginnings in Victorian England’s lowest tier, is initially unimpressed with the rural meagerness of Wemmick’s residence: â€Å"It appeared to be a collection of black lanes, ditches, and little gardens, and to present the aspect of a rather dull retiremen t. Wemmick’s house was a little wooden cottage in the midst of plots of garden†¦I think it was the smallest house I ever saw, with the queerest Gothic windows†¦and a Gothic door, almost too small to get in at.† (pg 192) As Pip later discovers, however, Walworth is, and represents, everything a rigid London occupational life is not: quaint, romantic, simultaneously thrilling and calming. Wemmick creates for himself simple pleasures at Walworth, which are small enough for him to maintain and appreciate: â€Å"The bridge was a plank, and it crossed a chasm about four feet wide and two deep. But it was very pleasant to see the pride with which (Wemmick) hoisted (the flag) up, and made it fast; smiling as he did so, with a relish, and not merely mechanically.† (pg 192.) By employing sufficient details to describe both Walworth’s charm and its supreme importance to Wemmick, Dickens conveys the extent to which Walworth allows Wemmick to shed the blackes t layers of inner London’s austere, demanding society, and become someone of whom no one in his conventional community would respect or approve.Dickens paints a bold and meaningful picture of the importance of social paradigms on the mentalities of 19th century Englishmen by creating a profound contrast between Wemmick’s language in his London profession and that in his country home of Walworth. While working in London by day, Wemmick communicates with his boss and clients in an entirely businesslike fashion, saying exactly what needs to be said to complete his job and take home money in his pocket. Completely wary of the opinions of fellow society members, he remains tight-lipped in matters that may in any way hinder his work or social standing. Upon arriving home to Walworth, however, his clipped speech and habitually limited responses transform into cheery banter, good-natured teasing and an obvious display of hospitality. While at work, Wemmick grimly dismisses the city in which he works by informing Pip, â€Å"You may be cheated, robbed, and murdered in London. But there are plenty of people anywhere who’ll do that to you.† (pg 158) By contrast, Wemmick’s diction assumes an undeniably brighter tone when he addresses his â€Å"Aged Parent† and boasts of his role as handyman at Walworth: â€Å"I am my own engineer, and my own carpenter, and my own plumber, and my own gardener, and my own jack of all trades. Well, it’s a good thing you know. It brushes the Newgate cobwebs away, and it pleases the Aged.† (pg 193) This division of expression is certainly no accident; Wemmick draws a line so prominent between his two vastly opposite ways of speaking that he classifies the submissions he feels discouraged from making in London as â€Å"Walworth sentiments,† only to be imparted in the liberation and ease of Walworth: â€Å"No; the office is one thing, and private life is another. When I go into the office, I leave the castle behind me, and when I come into the castle, I leave the office behind me. If it’s not in any way disagreeable to you (Pip), you’ll oblige me by doing the same. I don’t wish it professionally spoken about.† (pg 194) The seriousness with which Wemmick verbally addresses issues in his occupational life, when juxtaposed with his informal, lighthearted manner of addressing those same (or vastly different) matters in his residential life reveal his concerns over his reflection in the societal body’s eyes, and the extent to which he fights to preserve the segmentation of his two lives. Dickens effectively uses imagery to further display Wemmick’s daily metamorphosis from taciturn businessman to affable family man, as well as Wemmick’s struggle to live normally and appropriately in each habitat. Throughout the book, Dickens imparts the image of Wemmick’s mouth as a post office, widening and narrowing depending on his emotions and environment. While at Walworth no description of Wemmick’s mouth distinguishes it from any other, Pip observes in London how, â€Å"(Wemmick’s) mouth was such a post office of a mouth that he had a mechanical appearance of smiling.† Wemmick’s wide-mouthed, liberal emissions at Walworth remain controlled under the post office key in London, and just as Wemmick must release himself from his world of indulging pleasures within miles and minutes as he enters the world where none of this is possible, so must he regulate the similar operation of his post office: â€Å"By degrees, Wemmick got dryer and harder as we went along, and his mouth tightened into a post office again.† (pg 195) Through this prominent image, Dickens is able to humorously yet significantly display how careful and obedient regard of society’s social commandments, and the importance of isolating this obedience from the freedoms of home life, can manifest th emselves involuntarily in physical expressions. While Dickens consistently unveils the faults and inconsistencies of Victorian England society through the exaggerated conduct of most his characters, Wemmick serves as the primary, conscious observer of how these flaws become immersed in one’s being. By establishing a stable barrier between his occupation and dwelling, and thus building a mental machine to regulate his actions and expressions in both places, Wemmick proves himself to be aware of and responsive to what society demands of him, and what he demands of himself. Because of this separation, Wemmick is able to enjoy the life he feels compelled to live at home while still being able carry on a certain degree of shrouded respectability in London; if he neglects to do this, his worlds will inevitably become entangled, thereby both diminishing the enjoyments of rural life and betraying this life to the scrutiny of society. Whether this mutual isolation is necessary to pres erve personal identity, or whether identity is better formed with the influence of society, is open to reader interpretation; but Dickens undeniably, effectively poses this question through his use of details, language, and imagery in delineating Wemmick’s character.

Tuesday, May 26, 2020

The Good, the Bad and Personal Growth Essay Samples

The Good, the Bad and Personal Growth Essay Samples How to Get Started with Personal Growth Essay Samples? You'll observe a similar structure in several of the essays. Specific examples are almost always best to include in a thesis statement for your own personal development essay. Essays, generally, covers different topics. These seven sample essays respond to a wide variety of thought-provoking questions. Wherever and whatever it might be, you could make sure I will be there rain or shine. Someone learns the value of punctuality nightly. Bridget's essay is extremely strong, but there continue to be a couple little things that could be made better. Can be among the subsequent. The very first paragraph of your own personal development essay is the main one as you will want to grab your reader's attention and draw them in the essay. This section consists of two examples of fantastic college essays. Developmental changes are essential to ensure improvements in the total well-being of my career prospects. Be certain to take a look at this article for tips and samples for each one of the Common Application essay choices. The Number One Question You Must Ask for Personal Growth Essay Samples How they want people to take care of them. There are a lot of necessary things to keep in mind about a healthful relationship. Through my trainings I managed to learn to stay calm in stressful circumstances and be in a position to clear my mind to concentrate on the situation accessible. Unique things to various individuals, since the situation demanded. Planning is vital as it provides a medium for somebody to set goals and choose how they will need to be achieved. Education frequently occurs below the guidance of others, but might also be self-learning (Wikipedia). The improvement of interaction with different people was one of the principal goals of my PDP. There hasn't been any appreciable difference in my performance, which isn't satisfactory. The purpose is to attend a minumum of one social event every fourteen days. My inability to complete the reading program is bothering and discouraging. What Is So Fascinating About Personal Growth Essay Samples? It may be the food that you are eating. The chief reason why it's problematic for folks to leave relationships that have become insipid is simply a couple of think of private improvement as one of the main elements in fixing their partnership. The dearth of healthy and tasty school lunch selections has just come to be a problem in nearly every elementary middle and higher school throughout the nation. Pick a friend or relative and write about how you could enhance your connection with her or him. Write about why you're so very good at that one definite thing, and the way you can continue to be successful in that region of your life. Explain the vehicle connection better. Economic growth can be defined as an increase in the ability of the economy to generate distinctive products and services at distinct intervals. Due to the gradual change and maturation of the things around us, we find it tough to pause and reflect on the things which happen to our lives. Write about the qualities that individuals who demonstrate great personal growth show on a normal basis. This highlights a time management problem I need to take into consideration in the upcoming personal development program. In reality, economic growth is a quantitative indicator of financial development. You should have your reasons, and our principal concern is that you wind up getting an excellent grade. It is truly a method to discover new things and boost our understanding of the world. It may be an intellectual challenge, a research query, an ethical dilemma--anything that's of personal significance, regardless of the scale. Additionally, I meant to boost my social interactions inside and beyond the campus. We'll deal with them, and for an affordable price, as we understand that students generally don't have a great deal of money to spare. Many students leap right over the procedure component of the essay. They fixate on this part of how they're going to be evaluated.

Tuesday, May 19, 2020

Essay on Genocide of the Holocaust - 2735 Words

Genocide of the Holocaust Arthur Caplan, editor of When Medicine Went Mad: Bioethics and the Holocaust, states, The Holocaust, unlike many other instances of mass killing, was scientifically inspired, supervised and meditated genocide. Since all genocides are a grand-scale effort to systematically eradicate populations, their success hinges on having large portions of a nation going along with genocidal policy. The individuals in a society must be convinced of genocides legitimacy in their case, they need to forget that it is murder. Genocide obtains it legitimacy for the people of a nation from professionals, those knowledgeable individuals that provide the ideological, intellectual, and†¦show more content†¦Genocide would be necessary in order to maintain the health of Germany. In Mein Kampf, Hitler explains, Anyone who wants to cure this era, which is inwardly sick and rotten, must first summon up the courage to make clear the causes of the disease. Of course, he was referring to the Jews, Gypsies, and homosexuals that were contaminating the German race. This is the ideology behind the medical experimentation in sanitation and hygiene, that led to the gas chambers and euthanasia...all in an effort to rid the German race of it unwanted members. Medicine and science had played crucial roles both in fostering of Nazi ideology and in implementing the final solution. (Caplan) While medicine and science were being utilized, they had taken on a very different form. They were not treating individuals, but torturing them. It is obvious that the Hippocratic oath was either forgotten, or large, significant parts were completely ignored. The Hippocratic Oath (Original Version) I swear by Apollo the physician and Aesculapius, and Health, and All-heal, and all the gods and goddesses, that, according to my ability and judgement, I will keep this Oath and this stipulation. I will follow that system of regimen which, according to my ability and judgement, I consider for the benefit of my patients, and abstain from whatever is deleteriousShow MoreRelatedGenocides And Genocides Of The Holocaust1455 Words   |  6 PagesGenocides Occurring After the Holocaust The Holocaust was a mass murder of millions of individuals’ primary to and during World War II. â€Å"Only 54 percent of the people surveyed by the Anti- Defamation League (ADL) in a massive, global poll has ever heard of the Holocaust† (Wiener-Bronner). The Holocaust was from 1933-1945 and was run by German leader named Adolf Hitler. Hitler was a man who wanted to create his own race of people. Therefore to create this race, he wiped out anyone who did not haveRead MoreThe Genocide Of The Holocaust885 Words   |  4 Pages The Holocaust genocide lasted for approximately 4,482 days. There were nearly twelve years of planning and organizing the extermination of Jews in Europe. For most of those years, nearly all surrounding countries did not partake in assisting the survival of these Jews. Why? Why was there such insufficient help from countries around the world while the Holocaust had been occurring? Had other countries stepped in sooner to provide safety and rescue for the Jews, how different would history be? Read MoreThe Genocide Of The Holocaust1541 Words   |  7 Pageshuman history has existed, genocide as existed along with it. Even though the term itself was not coined until the 1940s by Raphael Lemkin in response to the Holocaust, the act of genocide has been occurring for millennia. In 146 BCE the first recorded act of genocide occurred with the Roman destruction of Carthage According to the Genocide Convention, genocide is defined as â€Å"the intent to destroy, in whole or in part, a nat ional, ethnical, racial or religious group†. Genocide happens for a multitudeRead MoreThe Genocide Of The Holocaust1313 Words   |  6 PagesGenocide is the destruction of an ethnic, racial, or religious group. The most famous genocide, conducted by the Germans, is the extermination of the Jewish population known as the Holocaust. There are other genocides such as the Armenian or Darfur genocide, but the Holocaust is the one talked about and studied the most around the world today. Museums exist in Washington D.C, Los Angeles, and parts of Europe that focus primarily on this dark time in history. Vast amounts of books, movies, and documentsRead MoreThe Genocide Of The Holocaust1881 Words   |  8 Pagesreligions for cultural differences. This horrible action is known as genocide and it has killed millions and millions of innocent people in our world. Genocide has happened many times throughout our history and one of the most well known is the Holocaust the deliberate killing of six million Jews. Sadly many people have witnessed genocide with their own eyes and wished they could have unseen it, such as Elie Wiesel, a Holocaust survivor. A few years ago was another event called Darfur occurred whichRead MoreThe Genocide And The Holocaust1198 Words   |  5 PagesThere have been several genocides in the past century. The Cambodian Genocide and the Holocaust are two of the great tragedies of the twentieth century. The Holocaust occurred in Germany and Eastern Europe. The Cambodian genocide took place in Cambodia. The Khmer Rouge was an overwhelming communist force that took Phnom Penh by surprise. In Cambodia, â€Å"21% of the population was killed. That is about 1.7 million people that lost their lives† (â€Å"Past Genocides†). There was little commotion or outcryRead MoreGenocide And The Holocaust772 Words   |  4 Pages Genocide is one of the most tragic events that can happen around the world. Identifying the stages is the most crucial part of stopping these horrible acts. The Bosnian Genocide and the Holocaust could have been prevented or stopped if the 8 stages were properly identified . There are 8 stages of genocide and the first stage is Classification. Classification is putting people into groups based on race, ethnicity, and religion. These groups usually are separated into the superior people and the inferiorRead MoreThe Genocide Of The Holocaust1372 Words   |  6 PagesYailene Gaona 7th Period Genocide Have you ever wondered how would it be like to experience being killed because of your hair , skin, eye, color? If you had to be killed for any of that it would be called genocide? By genocide they mean destruction of a nation, race, religion, or ethnic group. For example, in 1933 The Holocaust was occurring. Adolf Hitler was the one who began an army of Nazi s and they were the ones that would target Jews. They placed all of the Jews in concentration campsRead MoreThe Genocide Of The Holocaust1823 Words   |  8 Pages Genocide Genocide a word that brings forth the morbid image of barbed wire fences, trenches overflowing with bodies, malnourished men, women, and children, a depressing black sky. Genocides definition is â€Å"the deliberate killing of people who belong to a particular racial, political, or cultural group† (Merriam-Webster.com) True to its name genocide is a word that has the ability to cause war and leaves a hellish vision in its victims. Despite all of this the seeminglyRead MoreThe Holocaust Genocide1325 Words   |  5 Pages The Holocaust is one of the most gruesome and inhumane events to ever happen in the history of the world. The Holocaust took place during World War II. WWII was one event that was categorized as strictly good vs evil. At the beginning of the war America wanted to remain neutral because we had just come out of WWI and were working on rebuilding our economy. The United States was successful in remaining neutral until Japan bombed Pearl Harbor early on the mo rning of December 7. 1941. The United States

Friday, May 15, 2020

Chinese Wedding Dresses

At most Chinese weddings, the bride wears a qipao. At many Chinese weddings, the bride wears more than one Chinese wedding dress. Most brides opt for three dresses -- one red qipao, one white, Western-style wedding gown, and a third ball gown. The bride will begin the wedding banquet with one dress of these dresses. After three courses are served, the bride usually changes into her second Chinese wedding dress. After the sixth course, the bride will change once again into her third Chinese wedding dress. Some brides may opt for a fourth Chinese wedding dress to be worn as when greeting guests as they leave the wedding party. The groom typically wears one or two suits. While some grooms may opt for a traditional Zhongshan suit  or Mao suit, it is more likely to see older guests wearing a Mao suit. Instead, most grooms wear tuxedos or Western-style business suits. In addition to the Chinese wedding dresses worn on the wedding day, the bride and groom may either wear the same dresses for their Chinese wedding photos or wear a completely different set of clothing. Wedding guests usually wear bright colors especially red which symbolizes luck and wealth in Chinese culture. Guests should avoid white, which is reserved for the bride, and black, which is considered a somber color. More About Chinese Weddings How to Plan a Traditional Chinese WeddingAll About Chinese EngagementsWhat to Know About Chinese Wedding GiftsChinese Wedding Rituals

Wednesday, May 6, 2020

Parents Must Make Time for Their Children and...

In the past it was culturally accepted that a woman should not work or leave the house, especially when she had a child. As a mother, they had to stay home to take care of the house and the infant. Now a days woman are so busy with work, school, and social activities that they do not have time to take care of their family which is one of the most important issues in marriage and parenthood. In today’s life divorce is common among people which are a result of lacking communication and time. Same reasons can be dedicated to children when their parents do not put time and effort to educate them. Many problems such as: lack of self-confidence, feeling insecure, not being in control and many more can occur later on when a child is grown up and†¦show more content†¦By saying spending time it does not mean doing some sort of difficult or time consuming activity that would be hard or not affordable for the parents. Children can be happy by just being with their parents and by knowing that they have their parents’ attention on them. That has a positive influence because the child would not seek for attention from others or would not do something wrong so others will see or notice them. When no one is paying attention to a child they start finding ways to feel satisfied. TV is one of the main sources that now a day is used as the children’s first choice to complete the emptiness of their lack of attentions. Using video games as a source to spend time and get entertained seems wrong to some parents because some of their games are violent and not controllable and they do not have the time or nerves to control and argue with their children on the time they spend playing, so they rather TV shows. Just because TV channels are on their choice and they can choose to put whatever they feel convenient with seems more appropriate to them and they think it will not affect them as video games. For example, â€Å"if you look at the situation without un derstanding the social needs of the brain, it wouldn’t seem like it would be a problem to learn mainly from television† (Maia Szalavitz, Perry 215). Some parents do not pay attention to the needs of their children, and they keep them in their house byShow MoreRelatedCommunication: A Fundamental Part of the Early Childhood Teachers Role1725 Words   |  7 PagesThis essay will discuss communication as being a fundamental part of the early childhood teacher’s role. Educators will communicate with many people during the course of their day. Developing positive relationships through open communication is a strategy that will benefit teachers, parents and most importantly, their students. Teachers must establish limits and expectations for students, not only in the classroom, but within individual lessons. Behaviour management is an essential skill that willRead MoreThe Divorce Rate Of Married Couples880 Words   |  4 Pagesby the divorce are the children. Children of divorce are often guilty of blaming themselves for the marriage failure. My parents divorced when I was three years old, and, thankfully, I do not remember anything about their proceedings in the divorce. Their divorce has played a significant role in the aspect of the person I have become today. Divorce has become too important of an issue to ignore. According to the American Psychological Association, at least half of the children in the United StatesRead MoreEffective Communication in the Early Childhood Education Environment1517 Words   |  7 Pagesexperiences or were children required to conform to the teacher’s methods of teaching? If you answered the latter, do you think the former would improve the quality of education? The initial years of education are crucial to learning, development and growth, during these first years children’s experiences shape their learning methods and they are able to learn rapidly, for this, early childhood educators must use t eaching methods that are suitable for each child. Teachers must consider the attitudeRead MoreBridging Communication Gap Essay880 Words   |  4 PagesBridging Communication Gap The existence of communication gap between parents and children has served as a barrier for creating a healthy relationship in a family. Age gap is the primary reason for the prevalence of communication gap. This is divulged everyday in a local radio station that explicitly states, â€Å"If the music is too loud for you, then you’re too old.† Parents need to accept and respect if not appreciate the â€Å"music† of the younger generation. Similarly, children must learn toRead MoreEffective Communication in Early Childhood Education Essay1601 Words   |  7 PagesEffective communication creates a learning environment where students can learn according to their individual needs in a safe and accommodating environment. Think about your early childhood education (or your child’s early education), was it flexible to suit individual learning experiences or were children required to conform to the teacher’s methods of teaching? If you answered the latter, do you think the former would improve the quality of education? Pedagogues’ in all divisions of education shouldRead MoreSample Parental Involvement Essay1595 Words   |  7 Pages Parental Involvement: How Parents Contribute to School Success Kechia Howell Capella University ED 5320 August 4, 2017 As parents and teachers prepare for the new school year, there are many ways that parents and teachers can ensure that a student is successful throughout the school year. It is very imperative that teachers and parents form a relationship so that they may be on one accord when it comes to student success and making sure that the student is where he or she is supposedRead MoreUnderstanding Behavior And Family Dynamics1078 Words   |  5 Pages Week 2 Assignment: Communication Tia Durkin ECE355: Understanding Behavior Family Dynamics Professor Jeremiah 15 January, 2016 Communication is the cornerstone of any relationship, but between parent and child it is both unique and special. It is forged and developed through love and a special bond that can only be understood by them. It begins before a child is even born, and continues through their life. Communication is how we make our thoughts, feelings, needs, and thoughts knownRead MoreChildren Of Chronicly Ill Parents Case Study1415 Words   |  6 PagesThe Unacknowledged; Children of Chronically Ill Parents Debilitating and terminal diseases such as Multiple Sclerosis, Schizophrenia, Cystic Fibrosis, and certain types of Cancer are more likely to be diagnosed in a client’s twenties, thirties and forties. This event is devastating and life changing, especially if they are a parent. According to the Looking Glass Study in 2012, there are over four million parents that are disabled that have children under the age of eighteen that are livingRead MorePalliative Care for Children Essay1307 Words   |  6 PagesCare for Children: Enhancing the Quality of Life for a Child with a Life-Threatening Illness Melissa Spitler English Composition 2 Instructor Barckholtz May 17, 2010 Palliative Care for Children: Enhancing the Quality of Life for a Child with a Life-Threatening Illness â€Å"Each year in the USA about 500,000 children are coping with life-threatening illnesses† (Huang et al., 2010). The standard of care for children living with life-threatening conditions is vital for these children as wellRead MoreEssay Concepts of Communication in Parent Child Relationships1123 Words   |  5 Pages â€Å"Communication is the key† is a quote that is often repeated. In every single relationship communication is essential. Especially among parents and children. Communication between parent and child has always been important. Today, however, there is an even greater focus, especially in light of all the things children face at school and in everyday life. Without a parent knowing what is going on in the life and mind of their child, it is hard to really understand what they are going through. Communication

The Raven And American Romanticism Essay - 1292 Words

Kaylee Parker Kevin Stagg American Literature September 15, 2016 The Raven and American Romanticism The anonymous storyteller is busy reading a book when he hears somebody knock at his door. A faint thought comes to him that perhaps it was a guest, and he finds it better to let him in the following day because he was meditating over the demise of Lenore, his lover (Prince and Allan 4). Surprisingly, when he decides to open the door, he comes to nothing new except a sound echoing Lenore a reverberation from his thoughts. Coming back to his room, he again hears a knock and simply imagines that it was presumably the strong wind blowing from outside. A raven enters and expeditiously roosts upon a bust of Pallas over his entryway (Prince and Allan 3). The persona asks the bird of its name, the raven reacts, Nevermore. This left the narrator disturbed. Even though the poet employs several literary elements like symbolism, tone, and themes, the romanticism across the poem rekindles the overall atmosphere of the nineteenth century in America. The raven is one of the most revered literary pieces of Poe. The stylistic features and diverse dramatic qualities of the poem are appealing to the targeted audience. The repetitive use of the terms nothing more and nevermore build a fundamental internal rhyme scheme of a unique refrain. In the name Lenore and the word nevermore, Poe stresses the vowel O, which achieves a an atmosphere of loneliness and a tone of melancholic despondency (HamerShow MoreRelatedThe Raven and Romanticism Essay509 Words   |  3 PagesThe era of Romanticism spans from the late 1700s to the mid 1800s following the French Revolution; therefore, Romanticism encompasses characteristics of the human mind in addition to the particular time in history when these qualities became dominant in culture. Romanticism depicts an artistic movement which emerged from reaction against dominant attitudes and approaches of the 18th century. Romanticism established realism in literature through creativity, innovation, explorationRead MoreEssay on The Romantic Side of Edgar Allan Poe 1061 Words   |  5 Pageshas a trace of romanticism in it. Romanticism started around the 1800’s as a contradiction to rationalism. Rationalism was a thinking that attempted to use rational thinking and reason to solve the problems being faces at its time. Romanticism is basically the opposite of those thoughts. Romanticism is described as, a revolt against Rationalism that affected literature and the other arts, beginning in the late eighteenth century.(Elements of Literature, Page 1179). Romanticism bases its problemRead MoreThe Raven A Man By Edgar Allan Poe1737 Words   |  7 PagesRomanticism has dated back since the 1780’s, the literature behind Romanticism is full with emotion, passion and wildness. The characters in these passages are very distinguished, they are also iconic. The stories are usually set a unknown place for example in a cast le or in the woods, or they are set in a known place where something is out of the ordinary. There is something supernatural going on within the passage of writing. There are many thing that happen in the story that doesn’t happen inRead MoreIn The Years Before Abraham Lincoln Was Elected The Sixteenth1535 Words   |  7 Pagesan era that emphasized individualism, emotion, and nature. This era was called the â€Å"Romantic era†, or â€Å"Romanticism† as it is known today. Partially due to the Industrial Revolution, men and women had become intrigued by the advances in political structures and the rationalization of nature. This led to the rise of not only advancement in scientific endeavors and political evolution, Romanticism helped give birth to some of the greatest literary writers who have ever lived. From famous poets (likeRead MoreNature s Influence On The Development Of Literature1236 Words   |  5 PagesNature’s Influence on the Development of Literature Romanticism is a movement in the artistic world that originated from the eighteenth century with emphasis on inspiration and naturalness. The Romantic Movement’s beginning may be drawn back to the events of folklore and popular art which emerged as a result of the German Grimm brothers, Jakob and Wilhelm collecting tales and other academic professionals like Joseph Addison and Richard Steele, whose writings catered to clarity, it was time to departRead MoreAnalysis Of Edgar Allan Poe s The Raven1232 Words   |  5 Pages Edgar Allan Poe: The Raven Literature is a very powerful tool that is used to make a huge impact on society or in someone’s perspective. As complex as the world, literature can appear in many forms using unique vernacular that expresses human endeavors. In some cases, social reform is Transcendentalism is an American literary, philosophical movement, promoting the idea of independent progress. The central idea is the optimistic viewpoint of humanity. People, men and women equally, have knowledgeRead MoreThe Value Of Literature Courses1428 Words   |  6 Pagesnotice between American literature and literature from other parts of the world? (This question is based on your observations. A stronger argument can be made if you write in third person.) Literature from around the world is different and reflects thoughts, theories, attitudes, beliefs, and ideals that are relative to the time and culture. American literature, for example, has evolved over time as authors were writing about what was happening at the time. In particular, American Romanticism showed readersRead MoreEdgar Allan Poe Biography. By. Alyssa Marshall.1260 Words   |  6 PagesEra†, many of his stories genres are horror like â€Å" The Masque of The Red Death†, mystery such as â€Å" The Fall of The House of Usher†, lost love as in â€Å" The Raven†, and obsession such as â€Å" The Pit and The Pendulum†. Edgar’s poems and short stories are influenced by tragedies that happened through out his lifetime. Poe influenced not only American literature but literature around the world. He also influenced writers around the world such as Sir Conan Doyle, Fyodor Dostoevsky are just a few writers heRead MoreAnalysis Of Edgar Alla n Poe s The Raven And The Fall Of The House Of Usher 896 Words   |  4 PagesPoe is an extremely well known American writer and is famous for his horrific and mysterious works such as, â€Å"The Raven† and â€Å"The Fall of the House of Usher.† Poe was born in 1809 in Boston, Massachusetts in an era that seems to have many dark and ominous writers and pieces of literature originating from that time period. Poe is said to have launched the interest in many of the detective type stories that we read from modern day writers. â€Å"In the early 1800s, romanticism was the dominant literary modeRead MoreLiterary Romanticism : Literary Realism852 Words   |  4 PagesLiterary Romanticism in Contrast to Literary Realism Romanticism is a movement in the arts and literature that originated in the late 18th century, emphasizing inspiration, subjectivity, and the primacy of the individual. This particular movement focused on imagination and the interpretation of imagination by the individual. Romanticism primarily used symbolism to represent a much broader meaning than the object itself. In contrast, Realism attempts to describe life without idealization or romantic

Safety and Immunogenicity of Tetanus Diphtheria †Free Samples

Question: Discuss about the Safety and Immunogenicity of Tetanus Diphtheria. Answer: Introduction The discipline of immunology is incomplete without vaccination. The concept of vaccination was developed via the pioneering efforts of Edward Jenner and Louis Pasteur and has helped in the eradication of small pox and polio (Baron, 2014; Smith, 2013). Vaccination has also reduced the rate of occurrence of diseases like, measles, mumps, rubella, diphtheria, tetanus, pertussis (whooping cough) (Munoz et al., 2014). The development of vaccines begins with simple research. However, recent advancement in the field of immunology and molecular biology has paved the foundation of effective novel vaccine. B-cell and T-cell epitope have enabled immunologist to design new age vaccines which can maximise both the arms of immune system, active immunity and passive immunity (Patronov Doytchinova, 2013). There is always a need for development of vaccines against infectious diseases. Each year millions of people die round the world because of deadly viral disease, HIV-AIDS. According to World Health Organisation, 34 million in world is suffering from HIV (De Cock, Jaffe Curran, 2012). The first viral vaccine was designed via cloning a gene for major surface antigen of the Hepatitis B virus (HBsAg). The process undertaken was recombination, the recombinant yeast containing HBsAg has shown to generate protective antibodies against hepatitis B worldwide (Yu, 2016). Viral vaccines are generated out of inactivated virus or attenuated virus (alive but devoid of pathogenecity or devoid of disease causing capability) (Pica Palese, 2013). The failure of seasonal influenza vaccine to protect against the influenza infection had augmented the requirement for the discovery of the cross-reactive influenza vaccine that can elicit immunity against different subtypes of virus including newly emerging pandemic virus. The cross-protective vaccines like whole inactivated virus (WIV) vaccine, targets conserved internal antigens like the matrix protein or nucleoprotein of the virus and thereby preventing viral proliferation inside the body (Budimir et al., 2012). This inactivation can be done via several chemical compounds. The inactivated viral vaccine for West Nile virus (WNV) has been generated via the application of hydrogen per-oxide (H2O2) as an inactivating agent. The inactivated or attenuated vaccine thus produced is safe and immunogenic and is capable to protecting against WNV (Pinto et al., 2013). Other principal form of viral vaccines includes viral vector vaccines. Viral vector vaccines can be developed via using fowl poxvirus (FPV) and herpes virus of Turkey (HVT) as principal vectors carrying infectious laryngotracheitis virus (ILTV) genes. It is wide used in the poultry industry of USA for commercial purpose (Vagnozzi et al., 2012). Advantages and Disadvantages of Viral Vaccines Live-attenuated viral vaccine has several advantages. For example, live attenuated respiratory synctial virus (RSV) vaccine offers multiple advantages when used for immunization of young and infant children. This vaccine does not generate vaccine-associated enhanced RSV disease. Under the immunity wing, they generate innate, cellular and humoral immune response. This activation of immunity occurs in both systemic and local form. The generation of cellular and humoral immune response promote the generation of memory response thereby helping to fight against the recurrent infection in future. Moreover, this vaccine, does not cross-react with the passively acquired maternal antibody in the upper-respiratory tract (Karron, Buchholz Collins, 2013). Another form of the viral vaccines is RNA vaccines. The major genetic material of virus is RNA and hence it is used as an important component for viral vaccines. The RNA vaccines are made using mRNA transcript or via using self-amplifying RNA replicons. They have the potential to overcome the limitations associated with plasmid DNA and viral vectors (Ulmer, Mason, Geall, Mandl, 2012). Viral vector-based vaccines can increase the immunogenicity in the absence of an adjuvant. It also induces a robust cytotoxic T lymphocyte (CTL) response that helps in eliminating virus-infected cells (Ura, Okuda Shimada, 2014). Live attenuated vaccines have certain disadvantages. There lies a risk of these live attenuated vaccines to undergo recombination to generate virulent natural recombinants. For example, recombination between herpes viruses have been observed both in-vitro and in-vivo experimental conditions and thus has generated safety concerns regarding the application of the attenuated herpes virus vaccines, both for human and for veterinary use. The disease generating out of recurrent reactivation causes lifelong chronic infection (Lee et al., 2012). Vaccine production Hepatitis B remains a significant global health problems inspite of availability of effective and safe vaccine. The low cost, orally derived hepatitis b vaccine can alleviate problems like perpetuating infection-transmission cycle. 1. Cloning gene for HBsAg in yeast 2. Expressing the HBsAg under the presence of promoter 3. The recombinant yeast cells are cultivated in huge fermenters 4. HBsAg accumulate inside the cell 5. Yeast cells are harvested and then disrupted under high pressure 6. Release of recombinant HBsAg 7. Purified via concentional biochemical method 8. Recombinant hepatitis B vaccine induce production of portective antibodies against Hepatitis B virus Figure: Hepatitis B vaccine production via bioencapsulation of HBsAg (Source: Hayden et al., 2012) Disease associated with viral vaccines The most common secondary immuno-deficiency is acquired immunodeficiency syndrome of AIDS. It is caused by human immunodeficiency virus 1 (HIV-1). The rapid proliferation of the virus causes instant establishment of a systemic, large viral population, which is capable of dynamic adaptation under every immune selection pressure. These viruses always remain one-step ahead than the host immune system. Moreover, the virus replicates indefinitely in vast majority of infected individuals (Idele et al., 2014). Recent advancement in medical science has provided evidence that the initial stages of viral infection via mucosal transmission are comparatively vulnerable to immune intervention. This concept has lead to the development of vaccine strategy that can elicit responses against the early stages of viral infection (Picker, Hansen Lifson, 2012). Other diseases associated with viral vaccine are influenza, measles mumps rubella (MMR), chicken pox, hepatitis B (Bennett, Dolin Blaser, 2014). Here lies the importance of the viral vaccines as it helps in the treatment of the deadly diseases, which caused recurrent infections and are fatal. Conclusion Thus from the above discussion it can be concluded that viral vaccine occupy a significant portion of vaccine development in immunology. There are different types of virus vaccines used like live attenuate viral vaccines and viral vector vaccines. The successful use of the vaccines has been proved helpful to reduce the incidence of several diseases. However, more research studies are required to be undertaken in order to generate ethically safe viral vaccines for the treatment of deadly viral disease like HIV AIDS. References Baron, J. (2014).The Life of Edward Jenner MD(Vol. 2). Cambridge University Press. Bennett, J. E., Dolin, R., Blaser, M. J. (2014).Principles and practice of infectious diseases. Elsevier Health Sciences. Budimir, N., Huckriede, A., Meijerhof, T., Boon, L., Gostick, E., Price, D. A., ... de Haan, A. (2012). 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